Table 7 Multivariate analysis of HIV viral load and TCD4 cell count according to the expression of haplotypes in coinfected and monoinfected patients
From: MBL2 gene polymorphisms in HHV-8 infection in people living with HIV/AIDS
| Variables | HIV/HHV-8 n = 124 | HIV n = 213 | p valuea | OR (95% CI) |
|---|---|---|---|---|
| High expression haplotype | ||||
| First HIV viral load > 150,000 | 16 (34.8) | 14 (17.9) | – | Reference |
| First HIV viral load ≤ 150,000 | 30 (65.2) | 64 (82.1) | 0.1 | 2.1 (0.9–5.1) |
| Last HIV viral load detectable | 6 (13) | 17 (21.8) | – | Reference |
| Last HIV viral load undetectable | 40 (87) | 61 (78.2) | 0.2 | 0.4 (0.1–1.4) |
| First TCD4 cell count ≤ 350 | 34 (73.9) | 41 (52.6) | – | Reference |
| First TCD4 cell count > 350 | 12 (26.1) | 37 (47.4) | 0.1 | 2.0 (0.9–4.7) |
| Intermediate expression haplotype | ||||
| First TCD4 cell count ≤ 350 | 52 (75.4) | 76 (61.8) | – | Reference |
| First TCD4 cell count > 350 | 17 (24.6) | 47 (38.2) | 0.2 | 1.6 (0.8–3.1) |
| Last TCD4 cell count ≤ 350 | 15 (21.7) | 9 (7.3) | – | Reference |
| Last TCD4 cell count > 350 | 54 (78.3) | 114 (92.7) | 0.02 | 3.1 (1.2–7.6) |