Table 2 Analysis of inflammatory markers using one-way ANOVA with Tukey’s multiple comparison test
| Inflammatory marker (normal reference range) | Control mean (std. dev) [range] {% in normal range} | HIV negative-DVT mean (std. dev) [range] {% in normal range} | HIV positive-DVT mean (std. dev) [range] {% in normal range} | P value | Significant difference < 0.05 | ||
|---|---|---|---|---|---|---|---|
| Control vs. HIV negative-DVT | Control vs. HIV positive-DVT | HIV negative-DVT vs. HIV positive-DVT | |||||
| WCC (M: 3.9–10.4 × 109/L F: 3.9–12.6 × 109/L) | 5.3 (0.9) [4.0–6.7] {80.0} | 8.3 (2.4) [4.6–13.8] {94.3} | 10.0 (7.8) [4.0–33.4] {83.3} | 0.028 | – | Yes | – |
| CRP (< 10 mg/L) | 2.3 (2.4) [1–8] {100.0} | 60.9 (59.1) [1–193] {28.1} | 92.3 (76.6) [7–245] {8.3} | 0.003 | Yes | Yes | – |
| ESR (0–10 mm/h) | 5.0 (4.6) [1–15] {77.8} | 32.1 (36.6) [2–139] {46.9} | 46.4 (38.3) [9–116] {9.1} | 0.041 | – | Yes | – |
| Fibrinogen (2–4 g/L) | 2.6 (0.7) [1.7–4.3] {70.0} | 3.6 (1.3) [1–7] {67.7} | 3.4 (1.2) [1.5–5.3] {63.6} | 0.086 | – | – | – |
| Serum iron (M: 11.6–31.3 µmol/L F: 9.0–30.4 µmol/L) | 18.0 (9.0) [3–33] {90.0} | 8.7 (6.3) [2–29] {23.3} | 6.1 (3.6) [1.8–13] {10.0} | 0.0002 | Yes | Yes | – |
| Transferrin (M: 2.2–3.7 g/L F: 2.5–3.8 g/L) | 3.0 (0.7) [2.3–4.5] {90.0} | 2.4 (0.7) [2.3–4.5] {50.0} | 1.9 (0.9) [0.6–3.2] {33.3} | 0.007 | – | Yes | |
| Iron Saturation (M: 20–50% F: 15–50%) | 26.6 (15.2) [3–53] {70.0} | 17.7 (19.3) [3–97] {25.9} | 20.4 (28.3) [2–88] {12.5} | 0.505 | – | – | – |
| Ferritin (µg/L) (M: 26–388 µg/L F: 8–252 µg/L) | 147.6 (131.3) [3–412] {80.0} | 187.3 (237.6) [1.3–1101] {77.8} | 240.4 (159.2) [7–487] {55.6} | 0.620 | – | – | – |