Volume 12 Supplement 1

17th International Conference on Human Retroviruses: HTLV and Related Viruses

Meeting abstracts

Edited by Raymond Cesaire, Agnès Lézin and Jean-Marie Péloponèse Jr

Publication of this supplement was funded by EU PO-FEDER of Martinique. The Supplement Editors declare that they have no competing interests.

17th International Conference on Human Retroviruses: HTLV and Related Viruses. Go to conference site.

Trois Ilets, Martinique18-21 June 2015

Concatenated PDF 12S1

Page 2 of 3

Induction of APOBEC3B cytidine deaminase gene in HTLV-1 infected T-cells of ATL model mouse

Authors: Masakazu Tanaka, Jinchun Yao, Sung-il Lee, Yihua Ren, Norihiro Takenouchi and Jun-ichi Fujisawa

Citation: Retrovirology 2015 12(Suppl 1):P11

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Published on: 28 August 2015
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HTLV-1 inserts an ectopic CTCF-binding site into the human genome

Authors: Yorifumi Satou, Miyazato Paola, Ko Ishihara, Asami Fukuda, Kisato Nosaka, Takehisa Watanabe, Aileen Rowan, Mitsuyoshi Nakao and Charles RM Bangham

Citation: Retrovirology 2015 12(Suppl 1):P12

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Molecular characterization of heterogeneity in adult T-cell leukaemia/lymphoma

Authors: Huseini Kagdi, Aileen Rowan, Maria Antoinietta Demontis, Charles Bangham and Graham Taylor

Citation: Retrovirology 2015 12(Suppl 1):P13

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Published on: 28 August 2015
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Comparative analysis of gene expression patterns in the HTLV-1 infected T-cell clones

Authors: Anat Melamed, Hiroko Yaguchi, Aileen Rowan, Lucy Cook and Charles R M Bangham

Citation: Retrovirology 2015 12(Suppl 1):P14

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In vivo characterization of the BLV miRNA cluster

Authors: Anthony Rodari, Benoît Van Driessche, Nadège Delacourt, Caroline Vanhulle, Arsène Burny, Anne Van den Broeke, Olivier Rohr and Carine Van Lint

Citation: Retrovirology 2015 12(Suppl 1):P15

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Published on: 28 August 2015
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KIR genes and adult T-cell leukemia/lymphoma in patients infected with HTLV-1

Authors: Omar Melo, Eduardo Gotuzzo, Giovanni Lopez, Jason Rosado and Michael Talledo

Citation: Retrovirology 2015 12(Suppl 1):P16

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Published on: 28 August 2015
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In vitro basal T-cell proliferation and HTLV-1 proviral load among HTLV-1 subjects co-infected with Hepatitis C and/or HIV-1

Authors: Tatiane Assone, Tatiana Mitiko, Samara PC Gomes, Arthur Paiva, Michel Haziot, Jerusa Smid, Augusto Penalva de Oliveira, Philip J Norris and Jorge Casseb

Citation: Retrovirology 2015 12(Suppl 1):P17

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Published on: 28 August 2015
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Role of protein arginine methyltransferase 5 over-expression in HTLV-1-driven cellular transformation and leukemia

Authors: Amanda R Panfil, Jacob J Al-Saleem, Jesse Kwiek, Robert A Baiocchi and Patrick L Green

Citation: Retrovirology 2015 12(Suppl 1):P18

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Published on: 28 August 2015
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HTLV-1 infected CD4+T cells of HAM/TSP patients are susceptible to tunicamycin-induced endoplasmic reticulum stress

Authors: Daisuke Kodama, Ryuji Kubota, Toshio Matsuzaki, Hiroshi Takashima and Shuji Izumo

Citation: Retrovirology 2015 12(Suppl 1):P19

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Published on: 28 August 2015
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Analysis of the association between the sex and disease courses of 132 consequent patients with HTLV-1-associated myelopathy/Tropic spastic paraparesis (HAM/TSP)

Authors: Eiji Matsuura, Satoshi Nozuma, Ryuji Kubota, Shuji Izumo and Hiroshi Takashima

Citation: Retrovirology 2015 12(Suppl 1):P20

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Published on: 28 August 2015
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Phase I / II trial of dose adjusted EPOCH chemotherapy with bortezomib combined with integrase inhibitor therapy for HTLV-1 associated T-cell leukemia lymphoma

Authors: Lee Ratner, JC Ramos, Ariela Noy, Stefan Barta, Samir Parikh, Adrienne Phillips, Richard Ambinder, Dan Rauch, John Harding, Hicham Baydoun, Xiaogang Cheng, Breanna Caruso and Steven Jacobson

Citation: Retrovirology 2015 12(Suppl 1):P21

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Comparison of clinical, immunological and virological markers in patients with HTLV-1 / HIV-1 co-infection with those with mono-infection

Authors: D Dhasmana, A Puri, K Buell and G Taylor

Citation: Retrovirology 2015 12(Suppl 1):P22

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Molecular and clinical analyses of HTLV-1 subgroups associated with the risk of developing HAM/TSP.

Authors: Mineki Saito, Keiko Yasuma, Tadasuke Naito, Toshio Matsuzaki, Yuichi Mitobe, Yoshihisa Yamano, Hiroshi Takashima and Masao Matsuoka

Citation: Retrovirology 2015 12(Suppl 1):P23

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Tax as a therapeutic target in ATL

Authors: Zeina Dassouki, Umut Sahin, Hiba El Hajj, Florence Jollivet, Youmna Kfoury, Valérie Lallemand-Breitenbach, Olivier Hermine, Hugues de The and Ali Bazarbachi

Citation: Retrovirology 2015 12(Suppl 1):P24

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Chronic type adult T-cell leukemia-lymphoma after autolougous stem cell transplantation for ALK-negative anaplastic large cell lymphoma

Authors: Atae Utsunomiya, Masahito Tokunaga, Nobuaki Nakano, Ayumu Kubota, Shogo Takeuchi, Yoshifusa Takatsuka, Noriaki Yoshida and Masao Seto

Citation: Retrovirology 2015 12(Suppl 1):P25

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Biomarker to predict treatment response in patients with HTLV-1 associated myelopathy/Tropical spastic paraparesis (HAM/TSP)

Authors: Keiko Tamaki, Jun Tsugawa, Mika Matsuo, Yoshihisa Yamano and Yoshio Tsuboi

Citation: Retrovirology 2015 12(Suppl 1):P26

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Published on: 28 August 2015
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HAM/TSP patient treated with porcine cortex monosialoganglioside: clinical outcome and follow up

Authors: Camila Cánepa, Jimena Salido, Gabriela Pataccini, Matías Ruggieri, Sindy Fraile, Carolina Berini and Mirna M Biglione

Citation: Retrovirology 2015 12(Suppl 1):P27

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Published on: 28 August 2015
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Early hematopoietic stem cell transplantation improve treatment outcome of aggressive ATL.

Authors: Kaoru Uchimaru, Nobuhiro Ohno, Seiichiro Kobayashi, Ryuji Tanosaki, Shigeo Fuji, Takahiro Fukuda and Arinobu Tojo

Citation: Retrovirology 2015 12(Suppl 1):P28

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Neurolymphomatosis in patient with Adult T-cell leukaemia/lymphoma (ATLL)

Authors: Maki Yoshimitsu, Arata Hitoshi, Matsuura Eiji, Izumo Shuji and Takashima Hiroshi

Citation: Retrovirology 2015 12(Suppl 1):P29

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No evidence of association between Atherosclerosis, risk factors for cardiovascular disease and human T-cell lymphotropic virus type 1(HTLV-1) infection

Authors: Glauco Moniz de Aragão Dória, Viviana Olavarria Gallazzi, Ney Boa-Sorte, Maria Fernanda Rios Grassi and Bernardo Galvão-Castro

Citation: Retrovirology 2015 12(Suppl 1):P30

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Published on: 28 August 2015
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Anti-CCR4 monoclonal antibody KW-0761 (mogamulizumab) or investigator's choice in subjects with relapsed or refractory adult T-cell leukemia-lymphoma (ATL)

Authors: Adrienne Phillips, Paul Fields, Olivier Hermine, Graham P Taylor, Maria Delioukina, Steven Horwitz, Juan C Ramos, Jean-Côme Meniane, Stefan K Barta, Carlos Brites, Juliana Pereria, Brady Beltran, Luis Casanova, Farooq Wandroo, Tatyana Feldman, Karen Dwyer…

Citation: Retrovirology 2015 12(Suppl 1):P31

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Patterns of spinal cord atrophy in HTLV-1 associated myelopathy/ tropical spastic paraparesis (HAM/TSP)

Authors: Emily Charlip, Winston Liu, Raya Massoud, Jeanne Billioux, Breanna Caruso, Joan Ohayon, Govind Nair and Steven Jacobson

Citation: Retrovirology 2015 12(Suppl 1):P32

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Circulating exosomes as an enriched source for adult T-cell leukemia biomarkers

Authors: Sucharita Dutta, Elizabeth Broughman, Lifang Yang, Scott Peterson, Amol Prakash and O John Semmes

Citation: Retrovirology 2015 12(Suppl 1):P33

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Human T-cell lymphotropic virus type 1 (HTLV-1) infection among couples of a cohort followed up in São Paulo, Brazil

Authors: Arthur Paiva, Tatiane Assone, Samara SP Gomes, Jerusa Smid, Augusto Penalva de Oliveira and Jorge Casseb

Citation: Retrovirology 2015 12(Suppl 1):P34

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Incidence of tropical spastic parapesis/ HTLV-1 associated myelopathy/ (TSP/HAM) in patients followed in a Reference center in Salvador, Brasil

Authors: Izabel Bou Teixeira, Ney Boa-Sorte, Ramon Kruschewsky, Thessika Araújo, Maria Fernanda Grassi and Bernardo Galvão–Castro

Citation: Retrovirology 2015 12(Suppl 1):P35

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HTLV Tax repress nonsense mediated mRNA decay by inhibiting the ATPase activity of UPF1

Authors: Mocquet Vincent, Fiorini Francesca, Robin Jean-Philippe, LeHir Hervé and Jalinot Pierre

Citation: Retrovirology 2015 12(Suppl 1):P36

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Tuberculosis (TB) incidence in a cohort of individuals infected with human T-lymphotropic virus type 1 (HTLV-1) in Salvador, Brazil

Authors: Maria Fernanda Rios Grassi, Normeide Pedreira dos Santos, Monique Lírio, Afrânio Lineu Kritski, Maria Conceição Almeida Chagas, Leonardo Pereira Santana, Noilson Lázaro, Juarez Dias and Bernardo Galvão-Castro

Citation: Retrovirology 2015 12(Suppl 1):P37

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Unpasteurized milk from the bulk tank used for calf-feeding might increase incidence of BLV in dairy farms

Authors: Natalia G Porta, Juan P Jaworski, Rozana Galarza, Geronimo Gutierrez, Romina P Politzki, Irene Álvarez, Luis Calvinhos and Karina G Trono

Citation: Retrovirology 2015 12(Suppl 1):P38

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Assessment of functional capacity and flexibility of patients infected with HTLV-1

Authors: Isabelle Rocha Santos, Maria Fernanda Grassi, Ney Boa-Sorte, Ramon de Almeida Kruschewsky and Bernardo Galvão–Castro

Citation: Retrovirology 2015 12(Suppl 1):P39

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Patient satisfaction survey for HAM-net registrants

Authors: Kentaro Sato, Takayuki Kikuchi, Miyuna Kimura, Midori Komita, Kanade Shimada, Krumi Seki, Marika Tachibana, Naoko Yagishita, Ariella Coler-Reilly, Tomoo Sato, Natsumi Arayta, Miho Ishikawa, Mikako Koike, Yumi Saito, Hiroko Suzuki, Ayako Takata…

Citation: Retrovirology 2015 12(Suppl 1):P40

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Epidemiological features of BLV infection in Japan from 2012 to 2013

Authors: Ayumu Ohno, Shin-nosuke Takeshima, Mari Kikuya, Yuki Matsumoto and Yoko Aida

Citation: Retrovirology 2015 12(Suppl 1):P41

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Neutralizing antibodies in humans infected with zoonotic simian foamy viruses

Authors: Caroline A Lambert, Julie Gouzil, Réjane Rua, Edouard Betsem, Augustin Mouing Ondémé, Mirdad Kazanji, Richard Njouom, Antoine Gessain and Florence Buseyne

Citation: Retrovirology 2015 12(Suppl 1):P42

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Localization, quantization and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL

Authors: Goutham U Raval, Carlo Bidoia, Greta Forlani, Giovanna Tosi, Antoine Gessain and Roberto S Accolla

Citation: Retrovirology 2015 12(Suppl 1):P43

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HTLV-1 Tax induces Th1 master regulator T-bet and thus IFN-γ in CD4+CCR4+ T-cells of virus-associated myelopathy patients

Authors: Natsumi Araya, Tomoo Sato, Utano Tomaru, Ariella Coler-Reilly, Naoko Yagishita, Junji Yamauchi, Atsuhiko Hasegawa, Mari Kannagi, Hisanao Akiyama, Yasuhiro Hasegawa, Katsunori Takahashi, Yasuo Kunitomo, Yuetsu Tanaka, Atae Utsunomiya, Steven Jacobson and Yoshihisa Yamano

Citation: Retrovirology 2015 12(Suppl 1):P44

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T-cell receptor chain Vbeta subunit staining to quantify the malignant clone in adult T-cell leukemia

Authors: Aileen G Rowan, Paul Fields, Graham P Taylor and Charles RM Bangham

Citation: Retrovirology 2015 12(Suppl 1):P45

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Estimating rates of de novo infection and mitotic replication in HTLV-1 persistence: de novo infection continues after early infection

Authors: Daniel J Laydon, Vikram Sunkara, Charles RM Bangham and Becca Asquith

Citation: Retrovirology 2015 12(Suppl 1):P46

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Generation of virus-like particle as a vaccine strategy against bovine leukemia virus

Authors: Hiroyuki Otsuki, Shin-nosuke Takeshima and Yoko Aida

Citation: Retrovirology 2015 12(Suppl 1):P47

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Published on: 28 August 2015
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A novel bovine leukemia virus peptide vaccine targeting susceptible cattle-Production by 3-D modelling and nanotechnology

Authors: Yoko Aida, Jiyun Kim, Noriaki Okimoto, Junya Yamagishi, Seiichi Tada, Yoshihiro Ito and Shin-nosuke Takeshima

Citation: Retrovirology 2015 12(Suppl 1):P48

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Epitope mapping of CD8+ T cells on bovine leukemia virus Gag, Env and Tax protein in cattle with different bovine MHC DRB3 alleles

Authors: Lanlan Bai, Shin-nosuke Takeshima, Ayumu Ohno, Yuki Matsumoto, Emiko Isogai, Junko Kohara and Yoko Aida

Citation: Retrovirology 2015 12(Suppl 1):P49

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A novel bovine leukemia virus peptide vaccine targeting susceptible cattle-Estimating vaccine effectiveness using susceptible cattle constructed by fertilized ovum transplantation

Authors: Shin-nosuke Takeshima, Lanlan Bai, Pan He, Yuki Matsumoto, Junko Kohara, Tsunao Hirai, Takashi Omori, Tetsuo Nunoya, Yusuke Yamamoto, Takeo Hidaka, Kyoko Togamura, Kazuhiro Matoba and Yoko Aida

Citation: Retrovirology 2015 12(Suppl 1):P50

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Improving the methodology for the detection of proviral integration sites in the host genome via high throughput sequencing

Authors: Keith Durkin, Maria Artesi, Nicolas Rosewick, Ambroise Marçais, Olivier Hermine, Michel Georges and Anne Van den Broeke

Citation: Retrovirology 2015 12(Suppl 1):P51

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A critical role for IL-17RB signaling in HTLV-1 tax-induced NF-κB activation and T-cell transformation

Authors: Alfonso Lavorgna, Masao Matsuoka and Edward W Harhaj

Citation: Retrovirology 2015 12(Suppl 1):P52

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Suppression of HTLV-1 transcription by SIRT1 deacetylase

Authors: Dong-Yan Jin, Hei-Man Vincent Tang, Wei-Wei Gao, Chi-Ping Chan, Hidekatsu Iha and Kit-San Yuen

Citation: Retrovirology 2015 12(Suppl 1):P53

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Published on: 28 August 2015
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Akt activation by human T-cell leukemia virus tax oncoprotein

Authors: Mathew Cherian, Hicham Baydoun, Jacob Al-Saleem, Mamuka Kvaratskhelia, Patrick Green and Lee Ratner

Citation: Retrovirology 2015 12(Suppl 1):P54

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ORFI genetic polymorphisms in geographically distinct HTLV-1 infections

Authors: Fernanda Khouri Barreto, Ricardo Khouri, Filipe Ferreira de Almeida Rego, Maria Fernanda de Castro-Amarante, Izabela Bialuk, Cynthia A Pise-Masison, Bernardo Galvão-Castro, Antoine Gessain, Steven Jacobson, Genoveffa Franchini and Luiz Carlos Alcantara Jr

Citation: Retrovirology 2015 12(Suppl 1):P55

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Identification of TIGIT as an HBZ-induced gene by genome-wide analyses: its association with evasion of host defense

Authors: Keiko Yasuma, Jun-ichirou Yasunaga, Keiko Takemoto, Kenji Sugata, Norihiro Takenouchi, Masanori Nakagawa, Yutaka Suzuki and Masao Matsuoka

Citation: Retrovirology 2015 12(Suppl 1):P56

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Tax as a therapeutic target in ATL

Authors: Zeina Dassouki, Umut Sahin, Hiba El Hajj, Florence Jollivet, Youmna Kfoury, Valérie Lallemand-Breitenbach, Olivier Hermine, Hugues de The and Ali Bazarbachi

Citation: Retrovirology 2015 12(Suppl 1):P57

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The MHC Class II transactivator CIITA inhibits the persistent activation of NF-kB by Tax-1

Authors: Greta Forlani, Rawan Abdallah, Luisa Guidali, Roberto S Accolla and Giovanna Tosi

Citation: Retrovirology 2015 12(Suppl 1):P58

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Reciprocal communication between mesenchymal stem cells and leukemic cells: role of junctional complexes and exosomes in adult T-cell leukemia progression

Authors: Jamal El-Saghir, Tala Kanson, Farah Kouzi, Marwa Hussein and Marwan El-Sabban

Citation: Retrovirology 2015 12(Suppl 1):P59

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Localization, quantization and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL

Authors: Goutham U Raval, Carlo Bidoia, Greta Forlani, Giovanna Tosi, Antoine Gessain and Roberto S Accolla

Citation: Retrovirology 2015 12(Suppl 1):P60

Content type: Poster presentation

Published on: 28 August 2015
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17th International Conference on Human Retroviruses: HTLV and Related Viruses

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